Table 2 Univariate analysis of the factors associated with annual direct cost (¥) of patients with rare disease [Median (P25-P75)]
From: Analysis of economic burden and its associated factors of twenty-three rare diseases in Shanghai
Inpatients costs | Outpatients costs | Z | P | |
|---|---|---|---|---|
Age group (years) | ||||
≤ 14 | 2500 (1195–5778) | 82 (27–296) | −37.777 | < 0.001 |
15~64 | 3604 (1585–11,121) | 75 (28–209) | −51.787 | < 0.001 |
≥ 65 | 4104 (2300–7138) | 326 (171–781) | −24.486 | < 0.001 |
P | < 0.001 | < 0.001 | ||
Gender | ||||
Male | 3103 (1414–8156) | 102 (33–324) | −55.002 | < 0.001 |
Female | 2474 (1302–5559) | 77 (29–204) | −34.530 | < 0.001 |
p | 0.083 | < 0.001 | ||
Disease type | ||||
Endocrine and metabolic disease | 1757 (1055–2980) | 60 (24–145) | −43.484 | < 0.001 |
Skin disease | 3619 (2410–5971) | 17 (12–114) | −9.624 | < 0.001 |
Blood disease | 3337 (1405–12,208) | 92 (33–303) | −53.333 | < 0.001 |
Digestive disease | 318 (2025–5756) | 141 (59–352) | −25.282 | < 0.001 |
Bone disease | 4976 (1755–8913) | 145 (63–277) | − 8.597 | < 0.001 |
Cardiovascular disease | 4686 (2652–7390) | 78 (37–225) | − 24.458 | < 0.001 |
Immunological disease | 9228 (173–34,806) | 218 (4–1647) | −3.591 | < 0.001 |
Kidney disease | 12,530 (3793–16,519) | 153 (96–411) | −3.000 | 0.003 |
p | < 0.001 | < 0.001 | ||
Number of complications | ||||
1 | 3486 (1813–6479) | 68 (22–195) | −42.365 | < 0.001 |
2 | 1849 (870–3900) | 91 (38–243) | − 28.406 | < 0.001 |
3 | 1805 (962–4072) | 150 (70–390) | −21.015 | < 0.001 |
4 | 2610 (1404–6300) | 469 (219–2124) | −10.150 | < 0.001 |
5 | 3517 (1722–12,818) | 1937 (370–7832) | −3.764 | < 0.001 |
6 | 3984 (1893–17,492) | 1509 (710.60–11,237) | − 3.211 | 0.001 |
7 | 6310 (2934–21,999) | 8697 (1260–39,388) | − 0.26 | 0.979 |
8 | 5732 (3052–25,133) | 22,091 (4553–42,832) | −1.607 | 0.108 |
9 | 6691 (2758–40,848) | 18,297 (7526–59,551) | −1.248 | 0.212 |
≥ 10 | 13,962 (4995–41,706) | 44,324 (14191–89,266) | −4.156 | < 0.001 |
p | < 0.001 | < 0.001 | ||
Payment type | ||||
Social Security Card | 4083 (1892–11,676) | 71 (32–186) | −33.888 | < 0.001 |
Medicare Card | 2155 (1080–5345) | 64 (27–157) | −26.332 | < 0.001 |
Hospital Link Card | 3278 (1503–8006) | 90 (27–274) | − 58.033 | < 0.001 |
Hospital Self-Charge Card | 3506 (1415–14,791) | 287 (117–892) | −6.936 | < 0.001 |
Others | 1363 (837–3399) | 2158 (570–12,708) | − 0.234 | 0.815 |
p | < 0.001 | < 0.001 | ||
Total | 2953 (1425–7028) | 79 (30–228) | −81.944 | < 0.001 |