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Table 2 Sensitivity and specificity for the brain zones in the validation cohort. Sensitivity ranged from 100% for medulla oblongata to 0% for nodulus/uvula. Specificity was between 99% for frontoparietal cortex and 52% for midbrain. Additionally the 95% confidence interval was calculated for every value

From: An algorithm as a diagnostic tool for central ocular motor disorders, also to diagnose rare disorders

 

Midbrain

Pons

Medulla oblongata

Flocculus/ Paraflocculus

Vermis/ Fastigial Nucleus

Nodulus/ Uvula

Basal Ganglia

Fronto- parietal Cortex

Sensitivity:

30/39

28/34

4/4

34/54

14/54

0/54

22/28

5/11

76.9%

82.4%

100%

63.0%

25.9%

0.0%

78.6%

45.5%

95% CI

0.637–0.901

0.695–0.952

1.000–1.000

0.501–0.758

0.142–0.376

0.000–0.000

0.634–0.938

0.160–0.749

Specificity:

30/58

34/63

78/93

25/43

34/43

42/43

57/69

85/86

51.7%

54.0%

83.9%

58.1%

79.1%

97.7%

82.6%

98.8%

95% CI

0.389–0.646

0.417–0.663

0.764–0.913

0.434–0.729

0.669–0.912

0.932–1.000

0.737–0.916

0.966–1.000