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Table 2 Electrophysiological recordings

From: Peripheral myelin protein 2 – a novel cluster of mutations causing Charcot-Marie-Tooth neuropathy

  FAMILY A FAMILY B
  A.II-2 A.III-1 (proband) B.II-1 B.II-2 (proband)
Age at evaluation 34 years of age 20 years of age 30 years of age 35 years of age 37 years of age 46 years of age 37 years of age
Sensory CV (m/s) A (μV) DL (ms)   CV (m/s) A (μV) DL (ms) CV (m/s) A (μV) DL (ms) CV (m/s) A (μV) DL (ms) CV (m/s) A (μV) DL (ms) CV (m/s) A (μV) DL (ms)   CV (m/s) A (μV) DL (ms)  
Median NR NR NR   NE NE NE NR NR NR NR NR NR NR NR NR 54.9 5.9 NR   53.1 6.2 NR  
Ulnar NR NR NR   NE NE NE NR NR NR NR NR NR NR NR NR 53.1 2.4 NR   56.3 2.4 NR  
Sural NR NR NR   NE NE NE NR NR NR NR NR NR NR NR NR 43.3 6 NR   39.9 6.4 NR  
Motor CV (m/s) A (mV) DL (ms) FW-L (ms) CV (m/s) A (mV) DL (ms) CV (m/s) A (mV) DL (ms) CV (m/s) A (mV) DL (ms) CV (m/s) A (mV) DL (ms) CV (m/s) A (mV) DL (ms) FW-L (ms) CV (m/s) A (mV) DL (ms) FW-L (ms)
Median 12 3.1 5.13 NE NE NE NE 8.9 8.3 6.4 8 4.1 6.13 6.5 4.3 5.6 49.3 16.5 3.7 33.8 39.6 14 3.5 47.7
Ulnar 14.7 2.9 5.8 NE 21.9 12.5 8.8 11.1 6.2 7.9 11.7 2.7 5.9 12.5 2.7 6.4 56.3 10.1 2.6 35.4 45.3 10.3 3.3 43
Peroneal NR NR NR NE NR 4.3 14 NR NR NR NR NR NR NR NR NR 43.4 6.5 4.5 NE 30.6 0.7 4.1 NE
Tibial NR NR NR NE NE NE NE NR NR NR NR NR NR NR NR NR 47.5 9.5 4.5 60.3 35.9 4 4.2 76
  1. CV – nerve conduction velocity, DL – distal latency, FW-L – F-wave measurements, A – amplitude, NE- not examined, NR- not recorded