Table 6 Top 50 most commonly prescribed ATC codes in the early-diagnosed PKU populationa
ATC code or subcode | Category or subcategory | Early-diagnosed PKU patients (n = 161) % | Control group (n = 1,610) % | PR (95% CI) |
|---|---|---|---|---|
J | Antiinfectives for systemic use | 34.8 | 34.7 | 1.00 (0.80, 1.25) |
J01 | Antibacterials for systemic use | 32.9 | 33.9 | 0.97 (0.77, 1.22) |
N | Nervous system | 26.7 | 17.8 | 1.50 (1.14, 1.98) b |
N06 | Psychoanaleptics | 14.3 | 6.1 | 2.35 (1.54, 3.59) b |
N02 | Analgesics | 12.4 | 11.3 | 1.10 (0.71, 1.69) |
N05 | Psycholeptics | 8.7 | 2.2 | 3.89 (2.14, 7.06) b |
N03 | Antiepileptics | 3.7 | 0.7 | 5.00 (1.90, 13.14) b |
M | Musculo-skeletal system | 25.5 | 22.5 | 1.13 (0.86, 1.50) |
M01 | Antiinflammatory and antirheumatic products | 24.8 | 21.6 | 1.15 (0.86, 1.53) |
A | Alimentary tract and metabolism | 24.8 | 14.0 | 1.78 (1.32, 2.39) b |
A02 | Drugs for acid related disorders | 16.1 | 9.3 | 1.73 (1.18, 2.54) b |
A11 | Vitamins | 5.6 | 0.6 | 9.00 (3.71, 21.83) b |
H | Systemic hormonal preparations, excl. Sexual hormones and insulins | 16.8 | 12.7 | 1.32 (0.91, 1.90) b |
H03 | Thyroid therapy | 12.4 | 9.4 | 1.32 (0.86, 2.05) |
H02 | Corticosteroids for systemic use | 6.8 | 3.4 | 2.00 (1.07, 3.74) b |
R | Respiratory system | 15.5 | 15.1 | 1.03 (0.70, 1.50) |
D | Dermatologicals | 13.0 | 11.3 | 1.15 (0.76, 1.76) |
C | Cardiovascular system | 12.4 | 6.3 | 1.98 (1.26, 3.11) b |
C03 | Diuretics | 3.1 | 0.3 | 10.00 (2.93, 34.18) b |
G | Genitourinary system and sexual hormones | 11.8 | 7.7 | 1.53 (0.97, 2.41) |
B | Blood and blood forming organs | 7.5 | 3.5 | 2.11 (1.15, 3.84) b |
L | Antineoplastic and immunomodulating agents | 4.3 | 1.6 | 2.80 (1.23, 6.37) b |