Table 5 Comorbidity profilea of early-diagnosed adult PKU patients in 2015 in Germany
ICD-10-GM code | Comorbidity | Early-diagnosed PKU population (n = 161) % | Control population (n = 1,610) % | PR (95% CI) |
|---|---|---|---|---|
Z30 | Encounter for contraceptive management | 46.6 | 42.4 | 1.10 (0.92, 1.31) |
Z12 | Encounter for screening for malignant neoplasms | 35.4 | 30.1 | 1.18 (0.94, 1.47) |
N89 | Other noninflammatory disorders of vagina | 31.7 | 27.8 | 1.14 (0.90, 1.45) |
J06 | Acute upper respiratory infections of multiple and unspecified sites | 29.2 | 27.6 | 1.06 (0.82, 1.36) |
M54 | Dorsalgia | 26.1 | 22.6 | 1.15 (0.88, 1.52) |
Z01 | Encounter for other specified exam without complaint, suspected or reported dx | 23.6 | 15.5 | 1.52 (1.13, 2.05) b |
N94 | Pain and other condition associated with female genital organs and menstrual cycle | 18.0 | 12.9 | 1.39 (0.98, 1.98) |
R10 | Abdominal and pelvic pain | 15.5 | 13.0 | 1.19 (0.81, 1.74) |
J30 | Vasomotor and allergic rhinitis | 14.9 | 11.4 | 1.30 (0.88, 1.93) |
A09 | Infectious gastroenteritis and colitis, unspecified | 14.9 | 9.9 | 1.51 (1.01, 2.25) b |
N92 | Excessive, frequent and irregular menstruation | 14.3 | 10.7 | 1.34 (0.89, 2.00 |
F43 | Reaction to severe stress, and adjustment disorders | 13.7 | 7.8 | 1.75 (1.14, 2.67) b |
H52 | Disorders of refraction and accommodation | 13.0 | 10.8 | 1.21 (0.79, 1.84) |
F45 | Somatoform disorders | 13.0 | 9.3 | 1.40 (0.91, 2.15) |
F32 | Major depressive disorder, single episode | 12.4 | 9.9 | 1.25 (0.81, 1.93) |
E66 | Overweight and obesity | 11.8 | 7.1 | 1.67 (1.05, 2.63) b |
M79 | Other and unspecified soft tissue disorders, not elsewhere classified | 11.2 | 5.5 | 2.05 (1.27, 3.31) b |
F41 | Other anxiety disorders | 10.6 | 5.3 | 2.00 (1.22, 3.28) b |
M99 | Biomechanical lesions, not elsewhere classified | 10.6 | 8.7 | 1.21 (0.75, 1.96) |
T78 | Adverse effects, not elsewhere classified | 10.6 | 6.8 | 1.56 (0.96, 2.53) |
D22 | Melanocytic nevi | 10.6 | 8.9 | 1.19 (0.74, 1.91) |