Fig. 4From: A cost of illness study evaluating the burden of Wolfram syndrome in the United KingdomTornado plot: the twenty greatest cost drivers identified by the DSA. [a] Average cost of consumables. Upper estimate demonstrates the impact on the final COI by increasing the variable by 10%. Lower estimate demonstrates the impact on the final COI by decreasing the variable by 10%. COI cost of illness, DM diabetes mellitus, SNHL sensorineural hearing lossBack to article page