Fig. 1

Results of the Treatment Satisfaction Questionnaire for Medication (TSQM®-v.II) in patients with lipodystrophic syndromes treated by metreleptin. Rectangles represent 25th and 75th percentile values with median value depicted inbetween. Whiskers represent the lowest datum still within 1.5 interquartile range of the lower quartile, and the highest datum still within 1.5 interquartile range of the upper quartile (Tukey boxplot). a, scores for each item of the TSQMv.II self-questionnaire in all patients, b-e, scores for each item in the three adherence groups of patients (poor compliance (p), n = 5; acceptable compliance (a), n = 10; excellent compliance (e), n = 5). # p < 0.05 between a and e groups, * p < 0.05 between p and e groups and ** p < 0.05 between p and a groups