Table 1 Baseline characteristics of patients with unexplained conduction disorders and who underwent pacemaker implantation screened for AFD stratified by sex
From: Negative screening of Fabry disease in patients with conduction disorders requiring a pacemaker
Total (n = 188) | Males (n = 124) | Females (n = 64) | |
|---|---|---|---|
Age at pacemaker implantation, years | 63 ± 9 | 64 ± 7 | 62 ± 8 |
Medical history of neuropathy, n (%) | 5 (3) | 4 (3) | 1(2) |
Medical history of renal impairment, n (%) | 24 (13) | 20 (16) | 4 (6) |
Medical history of stroke, n (%) | 24 (13) | 19 (15) | 5 (8) |
Family history of SCD, n (%) | 14 (7) | 8 (7) | 6 (9) |
Family history of HCM, n (%) | 2 (1) | 1 (1) | 1 (2) |
Family history PMI, n (%) | 27 (14) | 18 (15) | 9 (14) |
Syncope, n (%) | 73 (39) | 45 (36) | 28 (44) |
Serum creatinine (mg/dl) | 1.03 ± 0.46 | 1.08 ± 0.44 | 0.94 ± 0.49 |
PR interval, ms | 189 ± 0.44 | 191 ± 57 | 186 ± 443 |
QRS interval, ms | 116 ± 28 | 120 ± 27 | 109 ± 286 |
LVH in ECG, n (%) | 40 (21) | 32 (26) | 8 (13) |
Interventricular septum, mm | 12 ± 3 | 12 ± 3 | 11 ± 3 |
LVEF, n (%) | 60 ± 10 | 59 ± 11 | 63 ± 8 |
α-Gal activity, μmol/L/h | 3.8 ± 1.7 | 3.9 ± 1.7 | 3.6 ± 1.6 |