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Fig. 3 | Orphanet Journal of Rare Diseases

Fig. 3

From: The impact of sirolimus therapy on lesion size, clinical symptoms, and quality of life of patients with lymphatic anomalies

Fig. 3

MRI and volumetric measurements for case number 7. An 8-year-old boy with KLA suffered from severe scoliosis, pain, thrombocytopenia, and coagulopathy. T2-weighted MRI of the chest demonstrates diffuse thickening of the interlobular septa and retroperitoneal soft tissue mass, which is the target lesion. a and b Pretreatment. c and d 6 months after administration of sirolimus. b and d show the volumetric measurements evaluated using the Digital Imaging and Communications in Medicine (DICOM) viewer (OsiriX)

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