| Anterior (n = 20) | Anterior & intermediate (n = 7) | Posterior (n = 5) | Any site (n = 24) | Total (n = 57) |
---|---|---|---|---|---|
Uveitis related primary outcome | 18 | 4 | 3 | 17 | 42 |
 Safety only | 0 | 0 | 0 | 0 | 0 |
 Single efficacy | 9 | 2 | 1 | 4 | 16 |
 Multiple separate efficacy | 7 | 2 | 2 | 11 | 22 |
 Composite efficacy | 2 | 0 | 0 | 2 | 4 |
Time to outcome measure in years (IQR) | 0.04–0.5 | 0.4–3 | 1–2.5 | 0.5–2 | 0.2–2 |
 Activity | 20 | 8 | 5 | 18 | 47 |
  ACC inactive SUN grade | 7 | 3 | – | 4 | – |
  ACC 2 step change SUN grade | 1 | 0 | – | 3 | – |
  Objective assessment AC Flare | 1 | 1 | 0 | 0 | – |
  Other AC assessment | 11 | 4 | 2 | 1 | – |
  Vitreous CC zero | – | 3 | 0 | 1 | – |
  Vitreous 2 step change SUN grade | – | 0 | 0 | 2 | – |
  Vitreous CC reduction | – | 0 | 2 | 3 | – |
  Objective assessment vitreous | – | 0 | 0 | 0 | – |
  Other vitreous assessment | – | 5 | 1 | 1 | – |
  Macular oedema (MO) | 3 | 2 | 3 | 13 | 21 |
  Objective assessment MO | 2 | 2 | 3 | 12 | 19 |
  Use of topical steroids | 1 | 1 | 1 | 4 | 7 |
  Use of systemic steroids | 0 | 2 | 1 | 4 | 7 |
 Visual acuity | 4 | 1 | 3 | 14 | 21 |
  Age appropriate measure | 0 | 1 | 1 | 6 | 8 |
Reproducible assessment of cataract | 0 | 0 | 0 | 0 | 0 |
Reproducible assessment of glaucoma | 0 | 0 | 0 | 0 | 0 |
Reproducible assessment of band keratopathy | 0 | 0 | 0 | 0 | 0 |
Vision related function | 1 | 0 | 0 | 2 | 3 |
Vision related quality of life | 1 | 0 | 2 | 0 | 3 |
Non-specific quality of life measure | 1 | 0 | 1 | 1 | 3 |
 Validated for use in children | 0 | 0 | 0 | 0 | 0 |