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Table 4 Characteristics of outcome measures in included trials by uveitis type

From: Under-utilisation of reproducible, child appropriate or patient reported outcome measures in childhood uveitis interventional research

  Anterior (n = 20) Anterior & intermediate (n = 7) Posterior (n = 5) Any site (n = 24) Total (n = 57)
Uveitis related primary outcome 18 4 3 17 42
Safety only 0 0 0 0 0
Single efficacy 9 2 1 4 16
Multiple separate efficacy 7 2 2 11 22
Composite efficacy 2 0 0 2 4
Time to outcome measure in years (IQR) 0.04–0.5 0.4–3 1–2.5 0.5–2 0.2–2
 Activity 20 8 5 18 47
  ACC inactive SUN grade 7 3 4
  ACC 2 step change SUN grade 1 0 3
  Objective assessment AC Flare 1 1 0 0
  Other AC assessment 11 4 2 1
  Vitreous CC zero 3 0 1
  Vitreous 2 step change SUN grade 0 0 2
  Vitreous CC reduction 0 2 3
  Objective assessment vitreous 0 0 0
  Other vitreous assessment 5 1 1
  Macular oedema (MO) 3 2 3 13 21
  Objective assessment MO 2 2 3 12 19
  Use of topical steroids 1 1 1 4 7
  Use of systemic steroids 0 2 1 4 7
 Visual acuity 4 1 3 14 21
  Age appropriate measure 0 1 1 6 8
Reproducible assessment of cataract 0 0 0 0 0
Reproducible assessment of glaucoma 0 0 0 0 0
Reproducible assessment of band keratopathy 0 0 0 0 0
Vision related function 1 0 0 2 3
Vision related quality of life 1 0 2 0 3
Non-specific quality of life measure 1 0 1 1 3
Validated for use in children 0 0 0 0 0
  1. ACC anterior cells count, SUN Standardised Uveitis Nomenclature, AC, anterior chamber, CC Cell count