Skip to main content

Table 1 Potential mimics of fibrous dysplasia by skeletal site

From: Best practice management guidelines for fibrous dysplasia/McCune-Albright syndrome: a consensus statement from the FD/MAS international consortium

Site

Differential diagnosis

General

Cancer (primary or secondary) or hematologic malignancy including solitary plasmocytoma sarcoma

 

Enchondromatosis

Simple bone cyst (unicameral)

Giant cell tumours

Aneurysmal bone cyst

Paget’s disease of bone

Neurofibromatosis type I

Cutaneous Skeletal Hypophosphatemia syndrome

Langerhans cell Histiocytosis

Melorrheostosis

Osteonecrosis

Osteitis Fibrosa Cystica (Recklinghausen)

Craniofacial bones

Ossifying fibroma

 

Fibro-osseous lesion

Cherubism

Aseptic mandibular osteitis (SAPHO syndrome)

Central giant-cell granuloma

Fronto-sphenoidal

Meningioma

Tibia

Adamantinoma and osteofibrous dysplasia