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Table 3 Laboratory examination results in 92 infants with congenital tuberculosis

From: Diagnosis and treatment of congenital tuberculosis: a systematic review of 92 cases

Examination

No. of patients tested

No. positive

Percentage (%)

Etiology

 PPD test

31

7

22.58

 Acid-fast staining of gastric juice smears

28

14

50.00

 Culture of tuberculosis bacilli in gastric juice

4

1

25.00

 Acid-fast staining of sputum smears

24

15

62.50

 Culture of tuberculosis bacilli in sputum

20

1

5.00

 Acid-fast staining of cerebrospinal fluid smears

12

1

8.33

 Culture of tuberculosis bacilli in cerebrospinal fluid

10

0

0

 Detection of tuberculosis DNA in sputum by PCR

18

12

66.67

Leukocyte count > 12 × 109/L

74

53

71.62

Neutrophil > 50%

65

47

72.31

Hemoglobin< 110 g/L

65

34

52.31

Platelet count< 100 × 109/L

50

11

22.00

C-reactive protein> 10 mg/L

38

25

65.79

Erythrocyte sedimentation rate > 20 mm/h

22

8

36.36

Serum alanine aminotransferase level > 40 U/L

50

15

30.00

Serum aspartate transferase level > 40 U/L

46

27

58.7

Serum total protein < 60 g/L

30

15

50.00

Serum albumin level < 35 g/L

32

20

62.50

Serum globin level < 25 g/L

31

11

35.48

Serum total bilirubin> 20 μmol/L

42

24

57.14

Serum direct bilirubin level > 7 μmol/L

34

18

52.94

Serum lactate dehydrogenase level > 250 U/L

20

20

100

Serum γ-glutamyl transpeptidase level > 50 U/L

22

14

63.64

Serum creatinine level > 40 μmol/L

22

4

18.18