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Table 3 Laboratory examination results in 92 infants with congenital tuberculosis

From: Diagnosis and treatment of congenital tuberculosis: a systematic review of 92 cases

Examination No. of patients tested No. positive Percentage (%)
Etiology
 PPD test 31 7 22.58
 Acid-fast staining of gastric juice smears 28 14 50.00
 Culture of tuberculosis bacilli in gastric juice 4 1 25.00
 Acid-fast staining of sputum smears 24 15 62.50
 Culture of tuberculosis bacilli in sputum 20 1 5.00
 Acid-fast staining of cerebrospinal fluid smears 12 1 8.33
 Culture of tuberculosis bacilli in cerebrospinal fluid 10 0 0
 Detection of tuberculosis DNA in sputum by PCR 18 12 66.67
Leukocyte count > 12 × 109/L 74 53 71.62
Neutrophil > 50% 65 47 72.31
Hemoglobin< 110 g/L 65 34 52.31
Platelet count< 100 × 109/L 50 11 22.00
C-reactive protein> 10 mg/L 38 25 65.79
Erythrocyte sedimentation rate > 20 mm/h 22 8 36.36
Serum alanine aminotransferase level > 40 U/L 50 15 30.00
Serum aspartate transferase level > 40 U/L 46 27 58.7
Serum total protein < 60 g/L 30 15 50.00
Serum albumin level < 35 g/L 32 20 62.50
Serum globin level < 25 g/L 31 11 35.48
Serum total bilirubin> 20 μmol/L 42 24 57.14
Serum direct bilirubin level > 7 μmol/L 34 18 52.94
Serum lactate dehydrogenase level > 250 U/L 20 20 100
Serum γ-glutamyl transpeptidase level > 50 U/L 22 14 63.64
Serum creatinine level > 40 μmol/L 22 4 18.18