From: Diagnosis and treatment of congenital tuberculosis: a systematic review of 92 cases
Examination | No. of patients tested | No. positive | Percentage (%) |
---|---|---|---|
Etiology | |||
PPD test | 31 | 7 | 22.58 |
Acid-fast staining of gastric juice smears | 28 | 14 | 50.00 |
Culture of tuberculosis bacilli in gastric juice | 4 | 1 | 25.00 |
Acid-fast staining of sputum smears | 24 | 15 | 62.50 |
Culture of tuberculosis bacilli in sputum | 20 | 1 | 5.00 |
Acid-fast staining of cerebrospinal fluid smears | 12 | 1 | 8.33 |
Culture of tuberculosis bacilli in cerebrospinal fluid | 10 | 0 | 0 |
Detection of tuberculosis DNA in sputum by PCR | 18 | 12 | 66.67 |
Leukocyte count > 12 × 109/L | 74 | 53 | 71.62 |
Neutrophil > 50% | 65 | 47 | 72.31 |
Hemoglobin< 110 g/L | 65 | 34 | 52.31 |
Platelet count< 100 × 109/L | 50 | 11 | 22.00 |
C-reactive protein> 10 mg/L | 38 | 25 | 65.79 |
Erythrocyte sedimentation rate > 20 mm/h | 22 | 8 | 36.36 |
Serum alanine aminotransferase level > 40 U/L | 50 | 15 | 30.00 |
Serum aspartate transferase level > 40 U/L | 46 | 27 | 58.7 |
Serum total protein < 60 g/L | 30 | 15 | 50.00 |
Serum albumin level < 35 g/L | 32 | 20 | 62.50 |
Serum globin level < 25 g/L | 31 | 11 | 35.48 |
Serum total bilirubin> 20 μmol/L | 42 | 24 | 57.14 |
Serum direct bilirubin level > 7 μmol/L | 34 | 18 | 52.94 |
Serum lactate dehydrogenase level > 250 U/L | 20 | 20 | 100 |
Serum γ-glutamyl transpeptidase level > 50 U/L | 22 | 14 | 63.64 |
Serum creatinine level > 40 μmol/L | 22 | 4 | 18.18 |