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Table 2 Main clinical manifestations in 92 infants with congenital tuberculosis

From: Diagnosis and treatment of congenital tuberculosis: a systematic review of 92 cases

  Age at onset  
Clinical manifestations ≤14 days n/N (%) > 14 days n/N (%) Total χ 2 P-value
Systemic manifestations
 Fever 31/41 (75.61) 43/51 (84.31) 74/92 (80.43) 1.094 0.296
 Cyanosis 17/41 (41.46) 22/51 (43.14) 39/92 (42.39) 0.026 0.872
 Jaundice 13/41 (31.71) 7/51 (13.73) 20/92 (21.74) 4.320 0.038
 Pallor 7/41 (17.07) 10/51 (19.61) 17/92 (18.48) 0.097 0.756
 Lymphadenopathy 4/41 (9.76) 4/51 (7.84) 8/92 (8.70) 0.000 1.0001
Respiratory system
 Respiratory distress 26/41 (63.41) 29/51 (56.86) 55/92 (59.78) 0.406 0.524
 Cough 17/41 (41.46) 33/51 (64.71) 50/92 (54.35) 4.949 0.026
 Pulmonary moist rales 12/41 (29.27) 20/51 (39.22) 32/92 (34.78) 0.991 0.319
 Triple restriction 5/41 (12.20) 10/51 (19.61) 15/92 (16.30) 0.915 0.339
 Foaming at the mouth 3/41 (7.32) 2/51 (3.92) 5/92 (5.43) 0.063 0.8011
Digestive system
 Hepatomegaly 28/41 (68.29) 35/51 (68.63) 63/92 (68.48) 0.001 0.973
 Splenomegaly 18/41 (43.90) 26/51 (50.98) 44/92 (47.83) 0.456 0.499
 Abdominal distention 10/41 (24.39) 11/51 (21.57) 21/92 (22.83) 0.103 0.749
 Poor appetite 2/41 (4.88) 8/51 (15.69) 10/92 (10.87) 1.738 0.1871
 Poor feeding 4/41 (9.76) 5/51 (9.80) 9/92 (9.78) 0.000 1.0001
 Vomiting 2/41 (4.88) 4/51 (7.84) 6/92 (6.52) 0.022 0.8831
 Diarrhea 2/41 (4.88) 4/51 (7.84) 6/92 (6.52) 0.022 0.8831
Nervous system
 Mental fatigue 6/41 (14.63) 11/51 (21.57) 17/92 (18.48) 0.726 0.394
 Seizures 5/41 (12.20) 5/51 (9.80) 10/92 (10.87) 0.001 0.9771
Skin 7/41 (17.07) 3/51 (5.88) 10/92 (10.87) 1.896 0.1681
  1. 1Continuity correction