Patient number
|
TTR mutation
|
Detection of variant TTR peaks
|
Theoretical mass changes (m/z)
|
Measured mass changes (m/z)
|
---|
1
|
Val30Met
|
+
|
+ 32.06
|
+ 31.95
|
2
|
Val30Met
|
+
|
+ 32.06
|
+ 31.62
|
3
|
Val30Met
|
+
|
+ 32.06
|
+ 31.58
|
4
|
Val30Met
|
+
|
+ 32.06
|
+ 31.30
|
5
|
Val30Met
|
+
|
+ 32.06
|
+ 32.08
|
6
|
Val30Met
|
+
|
+ 32.06
|
+ 31.21
|
7
|
Val30Met
|
+
|
+ 32.06
|
+ 32.51
|
8
|
Val30Met
|
+
|
+ 32.06
|
+ 31.97
|
9
|
Val30Met
|
+
|
+ 32.06
|
+ 31.20
|
10
|
Val30Met
|
+
|
+ 32.06
|
+ 31.53
|
11
|
Val30Met
|
+
|
+ 32.06
|
+ 33.22
|
12
|
Val30Met
|
+
|
+ 32.06
|
+ 32.07
|
13
|
Val30Met
|
+
|
+ 32.06
|
+ 31.77
|
14
|
Val30Met
|
+
|
+ 32.06
|
+ 32.45
|
15
|
Val30Met
|
+
|
+ 32.06
|
+ 31.33
|
16
|
Val30Met
|
+
|
+ 32.06
|
+ 32.46
|
17
|
Val30Met
|
+
|
+ 32.06
|
+ 30.75
|
18
|
Val30Met
|
+
|
+ 32.06
|
+ 31.29
|
19
|
Val30Met
|
+
|
+ 32.06
|
+ 32.73
|
20
|
Val30Met
|
+
|
+ 32.06
|
+ 32.57
|
21
|
Val30Met
|
+
|
+ 32.06
|
+ 31.22
|
22
|
Val30Met
|
+
|
+ 32.06
|
+ 31.54
|
23
|
Val30Met
|
+
|
+ 32.06
|
+ 31.35
|
24
|
Val30Met
|
+
|
+ 32.06
|
+ 31.82
|
25
|
Val30Met
|
+
|
+ 32.06
|
+ 31.72
|
26
|
Val30Met
|
+
|
+ 32.06
|
+ 31.30
|
27
|
Val28Ser
|
+
|
- 12.06
|
- 13.25
|
28
|
Val28Met
|
+
|
+ 32.06
|
+ 32.05
|
29
|
Gly47Arg
|
+
|
+ 99.13
|
+ 98.72
|
30
|
Thr49Ser
|
+
|
- 14.03
|
- 13.83
|
31
|
Thr49Ile
|
+
|
+ 12.05
|
+ 8.79
|
32
|
Gly53Glu
|
+
|
+ 72.06
|
+ 71.02
|
33
|
Thr60Ala
|
+
|
- 30.03
|
- 29.22
|
34
|
Glu61Lys
|
–
|
- 0.94
|
ND
|
35
|
Glu61Lys
|
–
|
- 0.94
|
ND
|
36
|
Glu61Lys
|
–
|
- 0.94
|
ND
|
37
|
Lys80Arg
|
+
|
+ 28.01
|
+ 27.76
|
38
|
Gly83Arg
|
+
|
+ 99.13
|
+ 98.77
|
39
|
Glu89Gln
|
–
|
- 9.90
|
ND
|
40
|
Ala97Gly
|
+
|
- 14.02
|
- 13.55
|
41
|
Tyr114Ser
|
+
|
- 76.10
|
- 78.98
|
42
|
Tyr114Cys
|
+
|
- 60.03
|
- 59.56
|
- Abbreviation: ND not detected