Fig. 3
Temporal trends of outcomes according to the year of the first surgery. With time, there was a decreasing trend in (a) mean number of open heart surgeries (OHS) per patient, (b) paravalvular leakage (PVL) development, (c) all-cause mortality, and (d) cardiac mortality. Please note that clinical outcome has markedly improved since 2008, when unique echocardiographic findings suggesting severe Behcet’s disease-related aortic regurgitation were clinically introduced