Table 1 Clinical profile of patients with sickle cell anemia evaluated for investigation of NP through the DN-4, LANSS and painDETECT scales
Variables | Patients (n = 83) | ||
|---|---|---|---|
DN-4 | LANSS | painDETECT | |
Prevalence of NP (%) | 32.5 | 26.5 | 19.3 |
Average age in years ± SD (interval) | 20.6 ± 4.9 (14–34) | ||
with NP | 23.2 ± 5.0 (14–34) | 22.1 ± 4.3 (14–29) | 24.7 ± 5.1 (15–34) |
without NP | 19.4 ± 4.4 (14–32) | 20.1 ± 5.1 (14–34) | 19.7 ± 4.4 (14–32) |
NP by age groups | p < 0.01 | p < 0.05 | p < 0.05 |
Teenagers (14–18 years old) | 18.5% | 18.2% | 12.5% |
Adults (19–34 years old) | 81.5% | 81.8% | 87.5% |
Male | 50.6% | p > 0.05 | |
Use of Hydroxyurea | 49.4% | p > 0.05 | |
with NP | 39% | 34.1% | 14.6% |
without NP | 61% | 65.9% | 85.4% |
Average of values ± SD | |||
Hemoglobin (g/dl) | p = 0.5 | p = 0.6 | p = 0.02 |
with NP | 9.5 ± 2.2 | 8.4 ± 0.9 | 7.9 ± 1.1 |
without NP | 8.8 ± 1.4 | 9.0 ± 1.6 | 9.3 ± 1.5 |
Reticulocytes Count (%) | p = 0.6 | p = 0.9 | p = 0.01 |
with NP | 10.8 ± 5.6 | 10.0 ± 6.9 | 13.8 ± 5.0 |
without NP | 9.2 ± 5.1 | 9.5 ± 5.0 | 7.7 ± 4.2 |
Number of self-reporting of depression | p = 0.6 | p = 0.01 | p = 0.5 |
with NP | 2 | 4 | 0 |
without NP | 3 | 1 | 5 |
Treatment for CP | 0 (0%) | ||