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Table 1 Clinical profile of patients with sickle cell anemia evaluated for investigation of NP through the DN-4, LANSS and painDETECT scales

From: Screening for neuropathic pain in patients with sickle cell disease: is a single assessment scale sufficient?

Variables Patients (n = 83)
  DN-4 LANSS painDETECT
Prevalence of NP (%) 32.5 26.5 19.3
Average age in years ± SD (interval) 20.6 ± 4.9 (14–34)
 with NP 23.2 ± 5.0 (14–34) 22.1 ± 4.3 (14–29) 24.7 ± 5.1 (15–34)
 without NP 19.4 ± 4.4 (14–32) 20.1 ± 5.1 (14–34) 19.7 ± 4.4 (14–32)
NP by age groups p < 0.01 p < 0.05 p < 0.05
    Teenagers (14–18 years old) 18.5% 18.2% 12.5%
    Adults (19–34 years old) 81.5% 81.8% 87.5%
Male   50.6% p > 0.05
Use of Hydroxyurea   49.4% p > 0.05
    with NP 39% 34.1% 14.6%
    without NP 61% 65.9% 85.4%
Average of values ± SD
Hemoglobin (g/dl) p = 0.5 p = 0.6 p = 0.02
    with NP 9.5 ± 2.2 8.4 ± 0.9 7.9 ± 1.1
    without NP 8.8 ± 1.4 9.0 ± 1.6 9.3 ± 1.5
Reticulocytes Count (%) p = 0.6 p = 0.9 p = 0.01
    with NP 10.8 ± 5.6 10.0 ± 6.9 13.8 ± 5.0
    without NP 9.2 ± 5.1 9.5 ± 5.0 7.7 ± 4.2
Number of self-reporting of depression p = 0.6 p = 0.01 p = 0.5
   with NP 2 4 0
   without NP 3 1 5
Treatment for CP 0 (0%)