Patient # | Age at start of treatment | Dosages | Comedications | AE | Vaccination status before therapy | Vaccination status during therapy |
---|---|---|---|---|---|---|
1 | 19 months | 2.5 mg once daily | VGB, MAD | Recurrent URTI / LRTI Increase of cholesterol / TG | Complete | NA |
2 | 14 months | 2.5 mg 3 times per week | VGB, STM, VPA | None | Complete | No live vaccines |
3 | 15 months | 2.5 mg once daily | LTG, VGB | Transient stomatitis | Complete | NA |
4 | 17 months | 2 mg once daily | LEV, VPA | Transient stomatitis | Complete | NA |
5 | 12 months | 3 mg once daily | OXC | None | NA | No live vaccines |
6 | 14 days | 0.3 mg two times per week | flecainide, propranolol | None | Incomplete | NA |
7 | 5 months | 1 mg daily | ACTH, OXC, VGB, TMP | Transient anemia | No vaccinations | NA |
8 | 14 months | 2.5 mg daily | different AEDs, TMP | Recurrent URTI / LRTI Increase of cholesterol / TG | Complete | NA |
9 | 7 days | NA | TPM, VGB, VPA, propanolol, melatonin | Recurrent infections Reduction of phosphate Increase of cholinesterase Increase of TG Increase of LDH | NA | Vaccinations under therapy |
10 | 2 months | NA | LEV, VGB, sotalol | Recurrent infections | NA | Vaccinations during 3 months pause of therapy |
11 | 7 days | 0.05 mg every other day | VPA, VGB, TPM, propranolol, propafenone | Worsening of infantile acne Increase of phosphate Increase of cholinesterase | NA | Vaccinations under therapy |
12 | 1 month | 0.03 mg/m2twice per day | LEV, VGB | Transient neutropenia UTI | NA | NA |
13 | 3 months | 0.1 mg twice per day | VGB, flecainide, metoprolol, amiodarone, metildigoxin | Transient neutropenia Recurrent URTI | NA | NA |
14 | 2 days | 1.5-2 mg/m2 daily | VGB, LEV, digoxin, TMP/SMX, nystatin | Increase of cholesterol / TG Transient lymphopenia | NA | No live vaccines |
15 | 2 days | 0.25 mg daily | TMP/SMX, nystatin | None | NA | No live vaccines |
16 | 7 months | 0.5 mg twice per day | PB, VGB | Recurrent infections | NA | No live vaccines |
17 | 10 months | 5 mg daily | OXC, VGB, KD | None | NA | No live vaccines |