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Table 8 Guidance statements for hip reconstruction, hip replacement and growth modulation surgeries

From: Recommendations for the management of MPS IVA: systematic evidence- and consensus-based guidance

Statement Percentage consensus
Hip reconstruction can be considered in paediatric patients with MPS IVA who exhibit hip pain, reduced walking and endurance related to hip disease, as well as abnormal radiographic findings
Evidence Grade: D (limited published evidence)
86%
Hip replacement can be considered in adult patients with MPS IVA who exhibit hip pain, reduced walking and endurance related to hip disease, as well as abnormal radiographic findings
Evidence Grade: D (limited published evidence)
100%
Growth modulation surgery is recommended for all patients with MPS IVA who have evidence of genu valgum and should be performed as early as possible during the period of growth
Evidence Grade: D (limited published evidence)
77%