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Table 11 Guidance statement for cardiac valve replacement

From: Recommendations for the management of MPS IVA: systematic evidence- and consensus-based guidance

Statement Percentage consensus
Cardiac (aortic, mitral) valve replacement should be considered in patients with MPS IVA who display symptomatic and severe valve stenosis or regurgitationa
Evidence Grade: C (level 4 studies)
  1. Post-consensus comments by the SC to be taken into consideration:
  2. aThe Ross procedure should not be employed in patients with MPS IVA [57]