Skip to main content

Table 3 Comparison of OFT, PBS and gene test results in patients with HS

From: Molecular diagnosis of hereditary spherocytosis by multi-gene target sequencing in Korea: matching with osmotic fragility test and presence of spherocyte

 

RBC membrane protein-encoding genes

No. of patients with mutation (%)

No. of patients without mutation (%)

OFT

(n = 47)

Positive

33 (70.2)

8 (17.0)

Negative

5 (10.6)

1 (2.1)

PBS

(n = 59)

Positive

46 (78.0)

8 (13.6)

Negative

4 (6.8)

1 (1.7)

  1. Abbreviation: OFT osmotic fragility test, PBS peripheral blood cell smear