Fig. 2
Kaplan–Meier curves for time to (a) premature tooth loss, (b) fracturea, (c) multiple fractureb, (d) gross motor/ambulation difficulties, (e) pain, and (f) surgery. Solid lines show the Kaplan–Meier estimation; grey shading denotes probability of being event-free between upper and lower 95% CI. Only patients who had been followed longitudinally for at least 1 year were included in this analysis. Patients were censored at first occurrence of the clinical symptom of interest, death, or loss to follow-up. aTime to first fracture among patients with one or more fractures. bTime to first fracture among patients with multiple fractures, defined as three or more. CI, confidence interval