Sample | Mortality cases/no. at risk | Person-years; annual mortality rate per 100 (95% CI) | Hazard ratios (95% confidence intervals) | E-value | |
---|---|---|---|---|---|
Crude | Adjusted | ||||
Premature death | |||||
Reference | 748,900/5451,951 | 71,559,947; 1.047 (1.044–1.049) | 1.0 | 1.0 | 1.0 |
PCT (total) | 158/612 | 8921; 1.771 (1.515–2.070) | 1.5 (1.3–1.8) | 1.5 (1.2–1.7) | 2.4 |
Familial PCT | 27/255 | 3933; 0.686 (0.471–1.001) | 0.7 (0.5–1.1) | 0.8 (0.1–1.1) | 1.0 |
Sporadic PCT | 64/255 | 3828; 1.672 (1.309–2.136) | 1.5 (1.2–1.9) | 1.4 (1.1–1.8) | 2.2 |
Unclassified PCT | 67/102 | 1160; 5.776 (4.546–7.339) | 2.6 (2.1–3-4) | 2.5 (1.9–3.1) | 4.4 |
Malignant neoplasms (C00–96) | |||||
Reference | 181,205/5,451,951 | 71,559,947; 0.254 (0.253–0.255) | 1.0 | 1.0 | 1.0 |
PCT (total) | 48/612 | 8921; 0.538 (0.405–0.714) | 1.4 (1.1–1.9) | 1.4 (1.0–1.9) | 2.2 |
Sporadic PCT | 23/255 | 3828; 0.601 (0.399–0.904) | 1.6 (1.0–2.4) | 1.5 (1.0–2.2) | 2.4 |
Familial PCT | 11/255 | 3933; 0.280 (0.155–0.505) | 0.9 (0.5–1.7) | 0.9 (0.5–1.6) | 1.0 |
Unclassified PCT | 14/102 | 1160; 1.207 (0.715–2.038) | 2.0 (1.2–3.4) | 1.8 (1.1–3.1) | 3.3 |
Diabetes mellitus (E10–14) | |||||
Reference | 11,826/5452,010 | 71,559,947; 0.016 (0.016–0.017) | 1.0 | 1.0 | 1.0 |
PCT | 3/612 | 8921; 0.034 (0.011–0.104) | 2.0 (0.7–6.3) | 1.7 (0.5–5.3) | 2.8 |
Ischemic heart disease (I20–25) | |||||
Reference | 5,451,951 | 71,559,947; 0.135 (0.134–0.136) | 1.0 | 1.0 | 1.0 |
PCT | 7/612 | 8921; 0.079 (0.037–0.165) | 0.6 (0.3–1.2) | 0.6 (0.3–1.2) | 1.0 |
Cerebrovascular diseases (I60-I69) | |||||
Reference | 57,639/5,451,951 | 71,559,947; 0.081 (0.080–0.081) | 1.0 | 1.0 | 1.0 |
PCT | 8/612 | 8915; 0.090 (0.045–0.179) | 1.2 (0.6–2.4) | 1.1 (0.6–2.3) | 1.4 |
Chronic obstructive pulmonary disease (J43–44) | |||||
Reference | 31,172/5,451,951 | 71,559,947; 0.043 (0.043–0.044) | 1.0 | 1.0 | 1.0 |
PCT | 7/612 | 8921; 0.078 (0.037–0.165) | 1.4 (0.6–2.9) | 1.4 (0.6–2.8) | 2.2 |
Diseases of the liver (K70–77, B15–19, E83.1) a | |||||
Reference | 4661/5,452,010 | 71,559,947; 0.007 (0.00–0.007) | 1.0 | 1.0 | 1.0 |
PCT | 6/612 | 8921; 0.067 (0.030–0.150) | 5.9 (2.7–13.2) | 5.5 (2.5–12.2) | 10.5 |
Renal failure (N17–19) | |||||
Reference | 6686/5,452,010 | 71,559,947; 0.009 (0.009–0.010) | 1.0 | 1.0 | 1.0 |
PCT | 2/612 | 8921; 0.022 (0.006–0.090) | 2.9 (0.7–11.8) | 2.9 (0.7–11.7) | 5.3 |
Drug and alcohol overdose (X40–49) b | |||||
Reference | 4961/5452,010 | 71,559,947; 0.007 (0.007–0.007) | 1.0 | 1.0 | 1.0 |
PCT | 7/612 | 8921; 0.078 (0.037–0.165) | 12.1 (5.8–25.5) | 9.9 (4.7–20.8) | 19.3 |