Serum endostatin levels are associated with diffusion capacity and with tuberous sclerosis- associated lymphangioleiomyomatosis

Table 3 Associations of TSC versus Sporadic LAM with subject characteristics

	Unadjusted OR (95% CI)	P value	Adjusted OR (95% CI)	P value
Age (10-year increase)
Sporadic	1.00	0.035	1.00	0.086
TSC	0.56 (0.31, 0.93)	0.035	0.54 (0.25, 1.04)	0.086
Endostatin (10-ng/mL increase)
Sporadic	1.00	0.0008	1.00	0.0015
TSC	2.22 (1.48, 3.82)	0.0008	2.51 (1.53, 4.87)	0.0015
Isolated Reduction in DLCO
Sporadic	1.00	0.016	1.00	0.29
TSC	8.86 (1.67, 68.17)	0.016	3.95 (0.33, 58.42)	0.29

Odds ratio associations were calculated via logistic regression models. Adjusted ORs were computed in models featuring age, serum endostatin concentration, AML, and isolated reduction in DLCO as covariates

ISSN: 1750-1172