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Table 2 Variable comparison for TSC LAM versus Sporadic LAM diagnosis

From: Serum endostatin levels are associated with diffusion capacity and with tuberous sclerosis- associated lymphangioleiomyomatosis

Variable TSC
N = 16
Sporadic
N = 44
Control
N = 25
P
Age (years) (mean ± SE) 41.6 ± 2.9 49.4 ± 1.8 39.4 ± 3.2 0.0031
FEV1 (%) (mean ± SE)5 90.9 ± 4.3 86.7 ± 3.6 0.462
FVC (%) (mean ± SE)5 99.6 ± 3.7 98.1 ± 3.0 0.752
DLCO (%) (mean ± SE)6 65.9 ± 5.9 67.7 ± 2.9 0.683
Endostatin (ng/mL) (mean ± SE) 54.2 ± 6.1 28.9 ± 2.1 30.1 ± 4.0 0.00071
AML
 No, n (%) 0 (0) 25 (56.8) 0.000054
 Yes, n (%) 16 (100) 19 (43.2)
Isolated Reduction in DLCO (< 60%) 6
 No, n (%) 11 (68.8) 39 (95.1) 0.0154
 Yes, n (%) 5 (31.2) 2 (4.9)
  1. 1 Kruskal-Wallis H test
  2. 2 Two-sample T test with unequal variance
  3. 3 Mann-Whitney U test
  4. 4 Fisher’s Exact Test
  5. 542 Sporadic LAM patients in analysis
  6. 641 Sporadic LAM patients in analysis