Table 1 Associations of serum endostatin concentration with patient characteristics
Variable | N | Mean Serum [Endostatin] (ng/mL) (SE) | Beta Estimate (95% CI) | P |
|---|---|---|---|---|
Diagnosisa | ||||
Control (Reference) | 25 | 30.1 (4.0) | ||
Sporadic LAM | 44 | 28.9 (2.1) | −1.2 (− 10.2, 7.9) | 0.80 |
TSC LAM | 16 | 54.2 (6.1) | 24.1 (12.5, 35.7) | 0.00008 |
Age (years)a | 84 | – | 0.15 (− 0.18, 0.48) | 0.36 |
FEV1 (%)b | 58 | – | −0.011 (− 0.27, 0.25) | 0.93 |
FVC (%)b | 58 | – | 0.018 (− 0.29, 0.33) | 0.91 |
DLCO (%)b | 57 | – | −0.28 (− 0.55, − 0.016) | 0.038 |
Isolated Reduction in DLCO (< 60%) b | ||||
No (Reference) | 50 | 31.8 (2.4) | 0.0029 | |
Yes | 7 | 55.9 (11.9) | 24.1 (8.6, 39.6) | |
AMLb | ||||
No (Reference) | 25 | 29.4 (2.8) | 0.044 | |
Yes | 35 | 40.1 (4.0) | 10.8 (0.31, 21.2) | |