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Table 1 Associations of serum endostatin concentration with patient characteristics

From: Serum endostatin levels are associated with diffusion capacity and with tuberous sclerosis- associated lymphangioleiomyomatosis

Variable N Mean Serum [Endostatin] (ng/mL) (SE) Beta Estimate (95% CI) P
 Diagnosisa
 Control (Reference) 25 30.1 (4.0)   
 Sporadic LAM 44 28.9 (2.1) −1.2 (− 10.2, 7.9) 0.80
 TSC LAM 16 54.2 (6.1) 24.1 (12.5, 35.7) 0.00008
 Age (years)a 84 0.15 (− 0.18, 0.48) 0.36
 FEV1 (%)b 58 −0.011 (− 0.27, 0.25) 0.93
 FVC (%)b 58 0.018 (− 0.29, 0.33) 0.91
 DLCO (%)b 57 −0.28 (− 0.55, − 0.016) 0.038
Isolated Reduction in DLCO (< 60%) b
 No (Reference) 50 31.8 (2.4)   0.0029
 Yes 7 55.9 (11.9) 24.1 (8.6, 39.6)
AMLb
 No (Reference) 25 29.4 (2.8)   0.044
 Yes 35 40.1 (4.0) 10.8 (0.31, 21.2)
  1. aModel includes all LAM patients and Control subjects
  2. bModel includes only LAM patients