Skip to main content

Advertisement

Table 4 Gonadal complications

From: The natural history of classic galactosemia: lessons from the GalNet registry

  n Valid n %
Female
 Puberty   134  
  Spontaneous puberty 69   51.5
  Induced puberty 65   48.5
 Primary ovarian insufficiencya 118 148 79.7
  Hormone replacement therapy 86 103 83.5
  Tried to conceive 16 95 16.8
  Successful pregnancyb 4 16 25.0
Male
 Delayed Pubertyc 3 63 4.8
 Cryptorchidism 3 54 5.6
 Fathered children 5 64 7.8
  1. aDiagnosed in women below the age of 40 years, with at least 40 months of amenorrhea and 2 independent, more than 1-month apart, FSH levels in the menopausal state
  2. bOf women who tried to conceive
  3. cA delayed puberty was defined as a lack of increase in testicle size by age 14