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Table 3 Neurological, cognitive and mental (psychiatric) complications

From: The natural history of classic galactosemia: lessons from the GalNet registry

  n Valid n %
Developmental delay infancy/childhood 167 320 52.2
 Motor 18   10.8
 Cognitive 66   39.5
 Motor and cognitive 83   49.7
 Language delayb 128 164 78.0
 Isolated language delay 37 170 21.8
Language and speech disordersa 192 289 66.4
 Speech defect 129 315 41.0
 Impairment in vocabulary 117 288 40.6
 Impairment in grammar 98 253 38.7
 Verbal dyspraxia 67 285 23.5
 Dysarthria 49 246 19.9
Neurological complicationsa 168 323 52.0
 Tremor 104 336 31.0
 General motor abnormality 86 319 27.0
 Ataxia 40 329 12.2
 Seizures 26 320 8.1
 Dystonia 24 318 7.5
Mental (psychiatric) and behavioral problemsa 128 288 44.4
 Anxiety disorder 67 300 22.3
 Depression 38 303 12.5
 ADHD 21 286 7.3
 Autism spectrum disorder 17 281 6.0
  1. aDefined as having at least one of the complications in that category, compared to having none of them
  2. bLanguage delay and motor and/or cognitive developmental delay