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Table 5 Acylcarnitine profile of LT group: pre-LT and post-LT and of non-LT group

From: Methylmalonic acidemia/propionic acidemia – the biochemical presentation and comparing the outcome between liver transplantation versus non-liver transplantation groups

LT(+)

Pre-LT

Post-LT

%

p

C3

14.41 ± 14.55

22.17 ± 8.71

+ 371.07%

0.05

C3:C2

2.046 ± 1.5673

0.9335 ± 0.3807

−32.41%

0.01*

MMA

373.20 ± 1004.09

97.63 ± 63.19

−79.99%

0.15

LT(−)

Initial

Latest

%

p compared with LT group

C3

11.18 ± 4.27

51.23 ± 51.07

+ 241.55%

0.12

C3:C2

0.8148 ± 0.27

1.1 ± 0.3920

+ 34.80%

*0.04

MMA

146.93 ± 433.87

109.39 ± 116.76

−17.68%

0.20

  1. *indicated significant difference compared to false positive group (p < 0.05)
  2. In LT(+) group: Pre-LT acylcarnitine level was collected 1 month before LT. Post-LT level was recruited at 4.1 ± 0.5 year after LT. In LT(−) group: Initial level indicates value at 1 month and latest values indicates at 3.9 ± 0.7 year
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Orphanet Journal of Rare Diseases

ISSN: 1750-1172