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Table 5 Dose-dependent treatment effects in acquired angioedema C1-inhibitor patients without (N = 6) and with (N = 8) anti-C1-INH autoantibodies

From: Angioedema due to acquired C1-inhibitor deficiency: spectrum and treatment with C1-inhibitor concentrate

  Patients without autoantibodies against C1-INH
(N = 6)
Patients with autoantibodies against C1-INH
(N = 8)
pdC1-INH dose (U) No. of patients No. of attacks Effectively treated patients Effectively treated attacks Non-effectively treated patients Non-effectively treated attacks No. of patients No. of attacks Effectively treated patients Effectively treated attacks Non-effectively treated patients Non-effectively treated attacks
500 3 338 3 337 1 1 7 102 5 33 3 69
1000 4 8 3 7 1 1 6 907 5 900 3 7
1500 0 0 0 0 0 0 2 4 1 1 1 3
2000 0 0 0 0 0 0 4 315 3 311 1 4
3000 0 0 0 0 0 0 1 1 1 1 0 0
  -. 346 344 2 2 1329 1246 83
  1. Note: The same patients may be represented as effectively treated and non-effectively treated
  2. C1-INH = C1-inhibitor