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Table 3 Effect of dose on plasma-derived C1-inhibitor concentrate efficacy

From: Angioedema due to acquired C1-inhibitor deficiency: spectrum and treatment with C1-inhibitor concentrate

 

500 U a

(N = 13)

≥ 1000 U a

(N = 11)

 

Mean (SD)

Body weight, kg

68.8 (24.0)

70.8 (12.6)

Time between attack onset and injection, hours

2.3 (1.1)

3.3 (4.2)

Shortening of attack with treatment, hours

53.1 (25.9)

58.8 (40.1)

Time between injection and resolution of symptoms, hours

27.6 (16.3)

21.9 (11.3)

  1. adose received in at least 90% of administrations
  2. SD = standard deviation