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Table 3 Effect of dose on plasma-derived C1-inhibitor concentrate efficacy

From: Angioedema due to acquired C1-inhibitor deficiency: spectrum and treatment with C1-inhibitor concentrate

  500 U a
(N = 13)
≥ 1000 U a
(N = 11)
  Mean (SD)
Body weight, kg 68.8 (24.0) 70.8 (12.6)
Time between attack onset and injection, hours 2.3 (1.1) 3.3 (4.2)
Shortening of attack with treatment, hours 53.1 (25.9) 58.8 (40.1)
Time between injection and resolution of symptoms, hours 27.6 (16.3) 21.9 (11.3)
  1. adose received in at least 90% of administrations
  2. SD = standard deviation