Table 2 Concomitant medications used during the study
From: Betaine anhydrous in homocystinuria: results from the RoCH registry
Concomitant medications | CBS deficiency, % | MTHFR deficiency, % | Cbl metabolism defects, % | |
|---|---|---|---|---|
Vit B6 responders | Vit B6 non-responders | |||
Carnitine | 11.1 | 12.24 | 33.33 | 80 |
Oral Vit B12 | 88.69 | 61.22 | 57.14 | 35.56 |
SC Vit B12 | – | – | 4.76 | 11.11 |
IM Vit B12 | – | 24.49 | 38.10 | 93.33 |
Folinic acid | – | 12.24 | 76.19 | 71.11 |
Vit B6 | 100 | 91.84 | 33.33 | 26.67 |
Folic acid | 100 | 83.67 | 38.10 | 46.67 |
L-methionine | – | 4.08 | 28.57 | 31.11 |
Other forms of betaine | – | 22.45 | 23.81 | 22.22 |
Methionine restricted diet | – | 87.76 | 28.57 | 35.56 |
MTHF | – | – | 19.05 | – |
Riboflavine | – | – | 28.57 | – |