Table 2 Proliferation index (Ki-67) and immunohistochemical staining of Islet-1, TTF1 and CDX2
Patient | Function | PNEN | Location | Ki-67 (%) | Islet-1 (%) | TTF1 (%) | CDX2 (%) |
|---|---|---|---|---|---|---|---|
A | F (WDHA-syndrome) | 1 | Head | 1 | +++ | + | – |
2 | Body | 1 | +++ | – | – | ||
3 | Tail | 2 | +++ | – | – | ||
B | NF | 1 | Head | 2 | +++ | – | – |
2 | Body | 8 | +++ | – | – | ||
3 | 1 | + | ++ | – | |||
4 | 1 | ++ | – | – | |||
5 | 1 | +++ | – | – | |||
6 | Tail | 1 | +++ | – | – | ||
C | NF | 1 | Duodenum | 1 | + | – | ++ |
2 | Head | 1 | +++ | – | – | ||
3 | Body | 1 | +++ | – | ++ | ||
4 | 2 | +++ | – | – | |||
5 | 1 | +++ | – | – | |||
6 | 1 | +++ | – | – | |||
7 | 1 | +++ | – | – | |||
8 | Tail | 1 | +++ | – | – | ||
9 | 1 | +++ | – | – | |||
10 | 1 | +++ | – | – | |||
11 | 1 | +++ | – | – | |||
12 | 1 | +++ | – | – | |||
13 | 1 | +++ | – | – | |||
14 | 1 | +++ | – | – | |||
15 | 1 | +++ | – | – | |||
D | F (Hyper-insulinism) | 1 | Body/Tail | 1 | +++ | – | – |
2 | 1 | +++ | – | – | |||
3 | 3 | +++ | – | – | |||
4 | 2 | +++ | – | – | |||
5 | 1 | +++ | – | – | |||
E | NF | 1 | Head | 1 | n.f. | n.f. | n.f. |
2 | 1 | +++ | – | – | |||
3 | Head/Body | 1 | +++ | – | – | ||
4 | 1 | +++ | – | – | |||
5 | 1 | +++ | – | – | |||
6 | 1 | +++ | – | – | |||
7 | 1 | +++ | – | – | |||
8 | Tail | 1 | +++ | – | – | ||
9 | 1 | +++ | – | – | |||
10 | 1 | +++ | – | – | |||
11 | 1 | +++ | – | – | |||
12 | 1 | +++ | – | – | |||
13 | 1 | +++ | – | – | |||
14 | 1 | +++ | – | – | |||
15 | 1 | +++ | – | – | |||
16 | 1 | +++ | – | – | |||
17 | 1 | +++ | – | – | |||
18 | 1 | +++ | – | – | |||
F | F (subclinical Hyper-insulinism) | 1 | Head/Body | 1 | +++ | – | – |
2 | 1 | +++ | – | – | |||
3 | 1 | +++ | – | – | |||
4 | 1 | +++ | – | – | |||
5 | 1 | +++ | – | – | |||
6 | 1 | +++ | – | – | |||
7 | 1 | +++ | – | – | |||
8 | 1 | +++ | – | – | |||
9 | 1 | +++ | – | – | |||
10 | 1 | +++ | – | – | |||
11 | 1 | +++ | – | – | |||
12 | 1 | +++ | – | – | |||
13 | Tail | 1 | +++ | – | – |