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Fig. 1 | Orphanet Journal of Rare Diseases

Fig. 1

From: Cerebellar involvement in warts Hypogammaglobulinemia immunodeficiency myelokathexis patients: neuroimaging and clinical findings

Fig. 1

Brain MRI, axial T2-weighted images through the lower cerebellum of a normal subject (a, b) and three WHIM patients (c-h). The same MR image is shown in each row: the MR image shown on the right column is presented with an overlying scheme of the foliation pattern (red lines). Panels a, b Normal subject: the cerebellar folia show a curvilinear course from posteromedial to anterolateral (“onion-like” configuration). Panels c, d. WHIM patient (P1) with normal “onion-like” orientation of the cerebellar folia. Panels e, f: WHIM patient (P5): the cerebellar folia show a straight course from posterolateral to anteromedial in a well ordered parallel pattern, confined to anterior portion of the cerebellar hemispheres. Panels g, h.WHIM patient (P4): the abnormal straight course of the cerebellar folia is more extensive, involving the whole hemispheres

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