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Fig. 5 | Orphanet Journal of Rare Diseases

Fig. 5

From: Analysis of LPI-causing mutations on y+LAT1 function and localization

Fig. 5

Effect of LPI mutations on arginine transport in transfected CHO cells. Transport activity of systems y+L was measured in CHO cells transfected with empty vectors (negative) and in cells transfected with plasmids carrying the indicated SLC7A7 mutations. y+L contribution was calculated as the difference between total transport and transport measured in the presence of 2 mM leucine. Data are means ± SEM of three different experiments, each performed in quadruplicate. * p < 0.05 vs negative

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