Table 2 Biological metabolic parameters of the whole group and the two subgroups according to the presence of an ultrasound goiter
Metabolic parameters | Whole group | UsGoiter | UsNonGoiter | p-value |
|---|---|---|---|---|
Number of patients (N; %) | N = 115 | 44 (38.3) | 71 (61.7) | |
Glucose metabolism | ||||
Abnormal glucose tolerance (n/N; %) | 16/112 (14.3) | 7/44 (15.9) | 9/68 (13.2) | .69 |
Diabetes (n/N; %) | 30/115 (26.1) | 10/44 (22.7) | 20/70 (28.6) | .45 |
Insulin therapy | 3/46 (6.5) | 0/17 | 3/29 (10.4) | .02 |
Metformin therapy | 9/46 (19.6) | 4/17 (23.5) | 5/29 (17.2) | .12 |
Insulin + Metformin | 3/46 (6.5) | 1/17 (5.9) | 2/29 (6.9) | .43 |
HbA1c (median (IQR); %) | 5.5 (5.2–5.8) | 5.4 (5.2–5.8) | 5.5 (5.3–5.7) | .39 |
OGTT (mean ± SD) | ||||
Glucose T0 (mg/dL) | 90.0 ± 15.0 | 90.0 ± 20.0 | 90.0 ± 10.0 | .60 |
Glucose T120 min (mg/dL) | 115.0 ± 50.0 | 140.0 ± 50.0 | 90.0 ± 50.0 | .048 |
Insulin T0 (mU/L) | 7.4 ± 6.1 | 8.1 ± 6.9 | 6.6 ± 5.2 | .11 |
Insulin T120 min (mU/L) | 42.5 ± 37.4 | 45.8 ± 31.5 | 39.2 ± 43.2 | .051 |
Lipids (mg/dL) | ||||
Total cholesterol (mean ± SD) | 200.0 ± 40.0 | 200.0 ± 40.0 | 200.0 ± 40.0 | .59 |
LDLc (median (IQR)) | 117 (96–140) | 110 (90–140) | 120 (100–140) | .96 |
HDLc (median (IQR)) | 50 (43–59) | 50 (40–60) | 50 (40–60) | .99 |
Triglycerides (median (IQR)) | 132 (97–192) | 140 (110–180) | 130 (90–220) | .89 |
Vitamin D | ||||
Median (IQR) (ng/ml) | 17 (12–28) | 17 (11–28) | 18 (13–30) | .15 |
n (< 30 ng/mL)/N (%) | 88/115 (76.5) | 35/44 (79.5) | 53/71 (74.7) | .51 |