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Fig. 4 | Orphanet Journal of Rare Diseases

Fig. 4

From: Linear scleroderma “en coup de sabre” with extensive brain involvement—Clinicopathologic correlations and response to anti-Interleukin-6 therapy

Fig. 4

Neuropathological Immunohistochemical Staining on Paraffin Embedded Formalin Fixed Tissue: a A MXA preparation highlights endothelium (× 100). b There is staining of vessels for C4d, a stable component of classic complement activation, consistent with a Gell and Comb’s type II immune reaction targeting endothelium (× 100)

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