Fig. 4From: Linear scleroderma “en coup de sabre” with extensive brain involvement—Clinicopathologic correlations and response to anti-Interleukin-6 therapyNeuropathological Immunohistochemical Staining on Paraffin Embedded Formalin Fixed Tissue: a A MXA preparation highlights endothelium (× 100). b There is staining of vessels for C4d, a stable component of classic complement activation, consistent with a Gell and Comb’s type II immune reaction targeting endothelium (× 100)Back to article page