Fig. 3
From: FGF23 and its role in X-linked hypophosphatemia-related morbidity
FGF23-receptor interactions. Schematic diagram of known and potential interactions between FGF23 (green circle) and its various receptors (blue and yellow). (left) FGF23 is known to bind in a KLOTHO (red)-dependent fashion to FGFRs 1, 2, and 3, (centre) and to bind to FGFR4 independently of KLOTHO. (right) KLOTHO-independent interactions with other receptors have also been proposed