| | N | Clinical progression | Stable score | Improvement score | Baseline (range) | Follow-up (range) | Progression rates per year |
|---|
All women | Symptomatic at baseline (N = 19) | Asymptomatic at baseline (N = 15) |
|---|
EDSS | 32 | 21 | 11 | 0 | 2.75 (0–6) | 3.5 (1.5–6) | 0.08 | 0.06 | 0.17 |
ALDS | 34 | 10 | 17 | 7 | 89.47 (71.92–89.47) | 89.47 (71.92–89.47) | 0.00 | 0.00 | 0.00 |
SF-36: PF | 34 | 19 | 1 | 14 | 0.22 (−2.66–1.16) | − 0.07 (−2.86–1.26) | 0.00 | −0.03 | 0.02 |
SF-36: PCS | 34 | 21 | 0 | 13 | 50.11 (17.26–62.36) | 49.16 (16.67–64.72) | − 0.21 | − 0.17 | − 0.37 |
- Progression rates were calculated with values unadjusted for covariates. The EDSS ranges from 0 (normal) to 10 (death). The ALDS scores are regression coefficients which were linearly transformed for interpretation, ranging from 10 (highest level of disability) to 89.47 (lowest level of disability). The SF-36 subdomain physical functioning is expressed in Z scores, ranging from −4 (lowest quality of life) to + 4 (highest quality of life). The SF-36 physical component summary score was linearly transformed to a range from 0 (lowest quality of life) to 100 (highest quality of life), with a mean of 50 and standard deviation of 10. ALDS = AMC Linear Disability Scale; EDSS = Expanded Disability Status Scale; N = number of women; PCS = physical component summary; PF = physical functioning
