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Table 3 PROMIS Instrument Analysis

From: Assessing disease experience across the life span for individuals with osteogenesis imperfecta: challenges and opportunities for patient-reported outcomes (PROs) measurement: a pilot study

Testing Population PROMIS® Measure N Mean (t-score) Std Dev 95% CI of the Mean Mean Significantly Different than 50 (p-value)?
Adult Anxiety 193 55.98 8.72 (54.74, 57.22) Yes (p < 0.001)
Depression 192 53.19 9.63 (51.82, 54.56) Yes ( p  < 0.001)
Fatigue 190 54.68 9.44 (53.33, 56.03) Yes ( p  < 0.001)
Pain Behavior 190 54.79 8.30 (53.60, 55.97) Yes (p < 0.001)
Pain Interference 188 57.50 9.64 (56.12, 58.89) Yes (p < 0.001)
Physical Function 102 43.91 7.48 (42.44, 45.38) Yes ( p  < 0.001)
Physical Function with Mobility Aid 85 35.82 6.13 (34.50, 37.14) Yes ( p  < 0.001)
Sleep Disturbance 188 53.19 9.15 (51.88, 54.51) Yes ( p  < 0.001)
Satisfaction with Participation in Social Roles 186 47.42 9.58 (46.03, 48.80) Yes ( p  < 0.001)
Parent Proxy Anxiety 56 54.91 9.91 (52.25, 57.56) Yes ( p  < 0.001)
Depressive Symptoms 54 50.60 9.12 (48.11, 53.09) No (p = 0.580)
Fatigue 52 50.85 12.00 (47.51, 54.19) No (p = 0.590)
Pain Interference 51 54.08 8.91 (51.57, 56.58) Yes (p = 0.004)
Mobility 52 33.98 11.44 (30.79, 37.16) Yes ( p  < 0.001)
Peer Relationships 52 42.09 10.85 (39.07, 45.11) Yes ( p  < 0.001)
  1. * Bold means p < 0.001