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Fig. 1 | Orphanet Journal of Rare Diseases

Fig. 1

From: Profiling of patient-specific myocytes identifies altered gene expression in the ophthalmoplegic subphenotype of myasthenia gravis

Fig. 1

Experimental design. Primary dermal fibroblasts from OP-MG (n = 10) and control MG (n = 6) donors were transduced with MyoD-adenovirus and differentiated into myocytes for either 48 h (early muscle model) or 5 days (late muscle model). At each differentiation time point, myocytes from each subphenotype were either left untreated or stimulated with 5% MG sera for 24 h (MG model) before RNA was harvested for analysis of gene expression by quantitative PCR

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Orphanet Journal of Rare Diseases

ISSN: 1750-1172