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Table 2 Comparison of serum fetuin-A, CRP and TNFα concentrations in patients with C1-INH-HAE with different attack localization

From: Serum fetuin-A, tumor necrosis factor alpha and C-reactive protein concentrations in patients with hereditary angioedema with C1-inhibitor deficiency

 

Symptom-free phase

Attack

p #

Subcutaneous attack (n = 12)

 Fetuin-A, mg/l

254 (200–273)

295 (260–325)

0.033

 CRP, mg/l

1.19 (0.99–6.16)

3.61 (0.79–4.44)

0.722

 TNFα, ng/ml

2.19 (1.70–2.83)

2.73 (1.75–3.71)

0.237

 D-dimer, μg/ml

0.52 (0.22–0.74)

1.15 (0.41–4.47)

0.110

Submucosal attack (n = 12)

 Fetuin-A, mg/l

265 (241–297)

286 (262–320)

0.308

 CRP, mg/l

1.84 (0.71–4.41)

3.64 (1.34–5.66)

0.272

 TNFα, ng/ml

2.58 (1.11–2.88)

3.17 (1.80–4.75)

0.310

 D-dimer, μg/ml

0.72 (0.17–2.19)

2.44 (1.07–16.52)

0.116

  1. Values in median (25–75) percentiles
  2. #Wilcoxon-test