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Table 1 Serum fetuin-A, CRP and TNFα concentrations in patients with C1-INH-HAE and healthy controls

From: Serum fetuin-A, tumor necrosis factor alpha and C-reactive protein concentrations in patients with hereditary angioedema with C1-inhibitor deficiency

  Symptom-free phase Attack Healthy controls p1 p2 p3
Fetuin-A, μg/ml 258 287 293 0.035 0.021 0.945
(224–285) (261–317) (263–329)
CRP, mg/l 1.25 3.57 1.95 0.303 0.247 0.528
(0.77–4.75) (0.93–4.73) (1.16–3.91)
TNFα, ng/ml 2.53 2.73 3.47 0.0008 0.207 0.166
(1.70–2.83) (1.80–3.71) (2.92–4.18)
D-dimer, μg/ml 0.52 2.44 0.42 0.405 0.023 0.006
(0.22–1.26) (0.67–5.36) (0.36–0.85)
  1. Values in median (25–75) percentiles
  2. p1: symptom-free phase vs. healthy controls, Mann-Whitney test
  3. p2: symptom-free phase vs. attack, Wilcoxon test
  4. p3: attack vs. healthy controls, Mann-Whitney test