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Fig. 2 | Orphanet Journal of Rare Diseases

Fig. 2

From: Tracking sex-dependent differences in a mouse model of CLN6-Batten disease

Fig. 2

Sex differences evident in Cln6nclf glial activation in brain. a Male Cln6nclf mice show enhanced microglial expression (CD68) in the somatosensory cortex at six months of age. b Genotypic differences in astrocyte activation are not present until six months of age, and are similar between the sexes. Images represent the six month time point only. N = 4–6, *p < 0.05, ***p < 0.001, ****p < 0.0001

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