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Table 5 Comparison of cardiac MR parameters in patients with different deletion sites in the dystrophin gene

From: Cardiac profile of the Czech population of Duchenne muscular dystrophy patients: a cardiovascular magnetic resonance study with T1 mapping

Segment

Group A

Group B

Group C

Group D

p-value of ANOVA

Age [years]

12.3 ± 4.9

14.7 ± 8.4

14.5 ± 4.8

14.9 ± 2.6

0.72

LV EF [%]

64.9 ± 7.3

63.5 ± 10.7

58.3 ± 13.7

46.0 ± 16.6

0.092

LVMi [g/m2]

37.8 ± 4.8

37.2 ± 10.9

38.9 ± 15.2

46.9 ± 7.5

0.60

LV EDVi [ml/m 2 ]

52 (49–55)

56 (43–64)

48 (36–63)

61 (48–72)

0.87

LV ESVi [ml/m 2 ]

18 (13–21)

21 (12–29)

16 (14–27)

35 (20–53)

0.42

LV SVi [ml/m 2 ]

31 (30–38)

34 (30–35)

29 (25–35)

26 (17–28)

0.13

Native T1 (anterior)

1029 ± 31

1082 ± 77

1067 ± 65

1045 ± 16

0.31

Native T1 (anteroseptal)

1029 ± 28

1052 ± 41

1032 ± 31

1036 ± 9

0.62

Native T1 (inferoseptal)

1029 ± 25

1054 ± 55

1033 ± 40

1059 ± 32

0.29

Native T1 (inferior)

1031 ± 32

1050 ± 44

1046 ± 58

1041 ± 35

0.88

Native T1 (inferolateral)

1040 ± 39

1037 ± 42

1057 ± 33

1058 ± 52

0.65

Native T1 (anterolateral)

1016 ± 38

1013 ± 36

1052 ± 68

1027 ± 43

0.38

Native T1 (global)

1029 ± 28

1049 ± 37

1047 ± 39

1045 ± 20

0.62

ECV (anterior)

0.262 ± 0.020

0.261 ± 0.013

0.269 ± 0.050

0.263 ± 0.039

0.97

ECV (anteroseptal)

0.255 ± 0.037

0.247 ± 0.019

0.259 ± 0.036

0.306 ± 0.103

0.28

ECV (inferoseptal)*

0.248 ± 0.031

0.237 ± 0.009

0.252 ± 0.036

0.321 ± 0.066 a.b

0.010

ECV (inferior)

0.250 ± 0.032

0.243 ± 0.008

0.265 ± 0.043

0.274 ± 0.031

0.53

ECV (inferolateral)*

0.256 ± 0.049

0.256 ± 0.045

0.293 ± 0.067

0.391 ± 0.116 a,b

0.022

ECV (anterolateral)

0.250 ± 0.040

0.253 ± 0.016

0.276 ± 0.048

0.344 ± 0.117

0.070

ECV (global)

0.253 ± 0.032

0.249 ± 0.008

0.269 ± 0.043

0.304 ± 0.047

0.17

  1. Variables with the Gaussian distribution are expressed as the mean ± standard deviation; those with different distribution are in italics as the median (lower quartile – upper quartile)
  2. Variables marked in bold and denoted with * have their ANOVA p-value < 0.05
  3. Post hoc test results: a – group D vs. group A: p < 0.05; b – group D vs. group B: p < 0.05
  4. LV left ventricle, EF ejection fraction, LVMi left ventricular mass index (g/m2), EDVi end-diastolic volume index, ESVi end-systolic volume index, SVi stroke volume index