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Table 5 Comparison of cardiac MR parameters in patients with different deletion sites in the dystrophin gene

From: Cardiac profile of the Czech population of Duchenne muscular dystrophy patients: a cardiovascular magnetic resonance study with T1 mapping

Segment Group A Group B Group C Group D p-value of ANOVA
Age [years] 12.3 ± 4.9 14.7 ± 8.4 14.5 ± 4.8 14.9 ± 2.6 0.72
LV EF [%] 64.9 ± 7.3 63.5 ± 10.7 58.3 ± 13.7 46.0 ± 16.6 0.092
LVMi [g/m2] 37.8 ± 4.8 37.2 ± 10.9 38.9 ± 15.2 46.9 ± 7.5 0.60
LV EDVi [ml/m 2 ] 52 (49–55) 56 (43–64) 48 (36–63) 61 (48–72) 0.87
LV ESVi [ml/m 2 ] 18 (13–21) 21 (12–29) 16 (14–27) 35 (20–53) 0.42
LV SVi [ml/m 2 ] 31 (30–38) 34 (30–35) 29 (25–35) 26 (17–28) 0.13
Native T1 (anterior) 1029 ± 31 1082 ± 77 1067 ± 65 1045 ± 16 0.31
Native T1 (anteroseptal) 1029 ± 28 1052 ± 41 1032 ± 31 1036 ± 9 0.62
Native T1 (inferoseptal) 1029 ± 25 1054 ± 55 1033 ± 40 1059 ± 32 0.29
Native T1 (inferior) 1031 ± 32 1050 ± 44 1046 ± 58 1041 ± 35 0.88
Native T1 (inferolateral) 1040 ± 39 1037 ± 42 1057 ± 33 1058 ± 52 0.65
Native T1 (anterolateral) 1016 ± 38 1013 ± 36 1052 ± 68 1027 ± 43 0.38
Native T1 (global) 1029 ± 28 1049 ± 37 1047 ± 39 1045 ± 20 0.62
ECV (anterior) 0.262 ± 0.020 0.261 ± 0.013 0.269 ± 0.050 0.263 ± 0.039 0.97
ECV (anteroseptal) 0.255 ± 0.037 0.247 ± 0.019 0.259 ± 0.036 0.306 ± 0.103 0.28
ECV (inferoseptal)* 0.248 ± 0.031 0.237 ± 0.009 0.252 ± 0.036 0.321 ± 0.066 a.b 0.010
ECV (inferior) 0.250 ± 0.032 0.243 ± 0.008 0.265 ± 0.043 0.274 ± 0.031 0.53
ECV (inferolateral)* 0.256 ± 0.049 0.256 ± 0.045 0.293 ± 0.067 0.391 ± 0.116 a,b 0.022
ECV (anterolateral) 0.250 ± 0.040 0.253 ± 0.016 0.276 ± 0.048 0.344 ± 0.117 0.070
ECV (global) 0.253 ± 0.032 0.249 ± 0.008 0.269 ± 0.043 0.304 ± 0.047 0.17
  1. Variables with the Gaussian distribution are expressed as the mean ± standard deviation; those with different distribution are in italics as the median (lower quartile – upper quartile)
  2. Variables marked in bold and denoted with * have their ANOVA p-value < 0.05
  3. Post hoc test results: a – group D vs. group A: p < 0.05; b – group D vs. group B: p < 0.05
  4. LV left ventricle, EF ejection fraction, LVMi left ventricular mass index (g/m2), EDVi end-diastolic volume index, ESVi end-systolic volume index, SVi stroke volume index