From: Comorbidity among HHT patients and their controls in a 20 years follow-up period
LPR data | Clinical data | |||||
---|---|---|---|---|---|---|
Cases | Controls | P value | Cases | Controls | i value | |
Total number of patients | 73 | 218 | 73 | 218 | ||
Patients with at least one relevant event registered | 73 | 214 | 62 | 90 | ||
Potentially HHT-related diagnoses | ||||||
Non-traumatic bleedings | 44 (60%) | 42 (19%) | < 0.001 | 47 (64%) | 16 (7%) | < 0.001 |
Bacterial infections | 40 (55%) | 84 (38%) | 0.015 | 29 (40%) | 61 (28%) | 0.06 |
Thromboembolisms | 8 (11%) | 38 (17%) | 0.19 | 9 (12%) | 29 (13%) | 0.83 |
Other vascular conditions | 14 (19%) | 48 (22%) | 0.610 | 5 (7%) | 32 (15%) | 0.0822 |
PAVMs | 6 (8%) | 0 | < 0.001 | 27 (37%) | 0 | < 0.001 |
Other HHT-related conditions | 53 (72%) | 0 | < 0.001 | 43 (59%) | 0 | < 0.001 |
Non-HHT-related conditions | 70 (95%) | 210 (96%) | 0.8646 | |||
Selected Subgroups of diagnoses | ||||||
Epistaxis | 27 (37%) | 4 (2%) | < 0.001 | 33 (45%) | 2 (1%) | < 0.001 |
Infections in joints and bones | 6 (8%) | 1 (0.5%) | < 0.001 | 5 (7%) | 0 | < 0.001 |