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Table 2 First event of diagnosis

From: Comorbidity among HHT patients and their controls in a 20 years follow-up period

  LPR data Clinical data
Cases Controls P value Cases Controls i value
Total number of patients 73 218   73 218  
Patients with at least one relevant event registered 73 214   62 90  
Potentially HHT-related diagnoses
 Non-traumatic bleedings 44 (60%) 42 (19%) < 0.001 47 (64%) 16 (7%) < 0.001
 Bacterial infections 40 (55%) 84 (38%) 0.015 29 (40%) 61 (28%) 0.06
 Thromboembolisms 8 (11%) 38 (17%) 0.19 9 (12%) 29 (13%) 0.83
 Other vascular conditions 14 (19%) 48 (22%) 0.610 5 (7%) 32 (15%) 0.0822
 PAVMs 6 (8%) 0 < 0.001 27 (37%) 0 < 0.001
 Other HHT-related conditions 53 (72%) 0 < 0.001 43 (59%) 0 < 0.001
 Non-HHT-related conditions 70 (95%) 210 (96%) 0.8646  
Selected Subgroups of diagnoses
 Epistaxis 27 (37%) 4 (2%) < 0.001 33 (45%) 2 (1%) < 0.001
 Infections in joints and bones 6 (8%) 1 (0.5%) < 0.001 5 (7%) 0 < 0.001
  1. The diagnoses were grouped according to clinical relevance for HHT. The time period covers January 1st 1995 to January 1st 2015
  2. The group PAVMs included all patients hospitalised while evaluated for PAVM, in 23 patients PAVM were seen at CT-scan or Pulmonary angiography, while 4 had positive contrast echocardiography, but no PAVM were identified at pulmonary angiography