Gynecologic assessment of 19 adult females with cartilage-hair hypoplasia – high rate of HPV positivity

Table 1 Cohort characteristics

	N
Age group (yrs)
19–30	7
31–40	3
41–50	4
51–60	0
> 60	5
Height (cm)
< 115	5
115–130	10
> 130	4
Reproductive health
Menarche (median, yrs)	12.5
Cycle length (variation, median, days)	21–60, 28
Menstrual flow
sparse	2
normal	15
heavy	2
Pregnancies	6/19
Births
0	14
1–2	1
> 2	4
Current hormonal therapy	5/19
Combined contraception pills	1
Progestin only -pills	2
Hormone replacement therapy	2
Immunodeficiency
Suseptibility to infections^a
Yes	9
Intermediate	4
Normal	6
Previous skin warts
Yes	4
No	14
Repeated genital infections	6/19
Previous malignancy^b	3
Leucocytes (× 10⁹/L) (range, median)	3.2–13.4; 5.6
Lymphocytes (× 10⁹/L) (range, median)	0.5–2.58; 1.22
Neutrophiles (× 10⁹/L) (range, median)	1.74–10.65; 3.37

^aYes = one or several episodes of otitis media and/or rhinosinuitits; Intermediate = pneumonia necessitating hospitalization and/or recurrent otitis media and/or rhinosinuitis requiring surgical treatment
^b1 squamous cell carcinoma,2 basal cell carcinomas