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Table 3 Age distribution in the 152 female patients with LAM and healthy women in previous studies

From: Comorbid connective tissue diseases and autoantibodies in lymphangioleiomyomatosis: a retrospective cohort study

Age

20s

30s

40s

50s

60s

70s

80s

Total

p-value *

Our study

16

(10.5%)

59

(38.8%)

55

(36.2%)

14

(9.2%)

7

(4.6%)

1

(0.7%)

0

(0.0%)

152

Hayashi [6]

43

(16.7%)

45

(17.5%)

45

(17.5%)

45

(17.5%)

45

(17.5%)

34

(13.2%)

0

(0.0%)

257

< 0.01 †

Hayashi [22]

178

(12.6%)

245

(17.3%)

232

(16.5%)

202

(14.3%)

308

(21.9%)

209

(14.8%)

35

(2.5%)

1409

< 0.01 †

  1. The percentage in parentheses represents the proportion in all cases
  2. In a previous study, those in their 20s had the highest ANA-positive rate (16.3%), followed by those in their 60s (14.9%), 30s (13.1%), 50s (11.9%), 70s (10.5%), and 40s (9.5%) for dilutions of 1:160 or higher. For dilutions of 1:40 or higher, healthy women in their 20s had the highest ANA-positive rate (39.9%), followed by those in their 30s (33.1%), 50s (31.2%), 60s (30.8%), 70s (30.1%), and 40s (28.4%) for dilutions of 1:40 or higher [22]
  3. *p-values were calculated for the distribution of age between this study and a previous study [6, 22]
  4. Mann-Whitney U-test
  5. Abbreviations: ANA anti-nuclear antibody