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Fig. 1 | Orphanet Journal of Rare Diseases

Fig. 1

From: Inhibitor clinical burden of disease: a comparative analysis of the CHESS data

Fig. 1

Physician-reported chronic hemophilia-pain by severity for PS-matched patients with and without inhibitors in CHESS studya. aPatients with current inhibitors were matched to patients who had never developed an inhibitor based on demographics (age, BMI, race) and comorbidity status using propensity scores stratified by hemophilia type. Matching was performed using a preset caliper size of 0.035 to maintain the maximum sample size using the smallest caliper width. bP-value refers to the difference in the proportion of patients with moderate to severe pain between cohorts and was derived from the McNemar’s test for categorical variables; p < .05 indicates statistical significance. Abbreviations: BMI, body mass index; CHESS, Cost of Haemophilia across Europe – a Socioeconomic Survey; PS, propensity score

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