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Table 1 Demographic characteristics (age, gender) and descriptive data by syndrome group

From: Using Bayesian methodology to explore the profile of mental health and well-being in 646 mothers of children with 13 rare genetic syndromes in relation to mothers of children with autism

  AS ASD CdLS DS FXSa PMS PWS RTTa RTS SMS Soto TSC 1p36 8p23 Total
n 28 66 44 29 102 31 101 87 47 20 38 71 26 22 712
Child mean age (sd, range) 10.9
3.3 (3–15)
15.5 6.5
(6–42)
12.8
8.2 (2–45)
25.4
11.8 (8–45)
15.0
8.2 (2–42)
11.3
8.4 (2–37)
12.2
8.1 (2–45)
20.1
10.2 (4–47)
21.3
10.5 (6–53)
11.6
7.2 (3–32)
15.3
9.3 (2–43)
18.8
10.7 (2–50)
10.9
8.9 (2–39)
10.8
5.5 (4–21)
15.2
9.5 (2–53)
% Male child 46.4 86.4 47.7 53.3 100 45.2 52.3 0 55.3 60 68.4 60.6 78.6 68.2 57.0
Maternal mean age (sd) 40.8
4.9
47.9
6.8
45.1
9.1
59.1
12.3
45.6
9.5
42.3
9.9
44.5
8.5
50.7
9.2
49.8
9.9
43.7
8.5
46.3
8.3
48.1
10.3
41.2
10.8
39.6
6.1
46.6
9.8
Speech % verbal 32.1 92.4 68.2 100 94.2 38.7 98 83 80 92.1 76.1 57.7 91.9 82.3
Hearing % normal 92.9 98.5 56.8 58.6 97.1 90.1 99.0 80.9 55 76.3 94.4 61.5 90.9 87.3
Vision % normal 85.7 86.4 63.6 43.3 88.3 71.0 73.3 51.1 75.0 73.7 88.7 26.9 45.5 74.4
Mobility % mobile 39.3 92.4 54.5 100 86.4 71 78.2 74.5 70 81.6 78.9 46.2 59.1 76.6
Self-help % able/partly able 14.3 89.2 40.9 90 88.2 22.6 78.2 80.9 60 84.2 66.2 42.3 59.1 70.4
  1. aGender distribution can be explained in these groups as only males with FXS were recruited and RTT almost exclusively affects females
  2. AS Angelman Syndrome, ASD Autism Spectrum Disorder, CdLS Cornelia de Lange syndrome, DS Down Syndrome, FXS Fragile-X Syndrome, PMS Phelan McDermid Syndrome, PWS Prader-Willi syndrome, RTT Rett Syndrome, RTS Rubenstein Taybi syndrome, SMS Smith Magenis Syndrome, TSC Tuberous Sclerosis Complex, 1p36 1p36 deletion syndrome, 8p23 8p23 deletion syndrome