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Table 5 Number of Responders Meeting and not Meeting DRI and Laboratory Reference Ranges

From: One-year follow-up of B vitamin and Iron status in patients with phenylketonuria provided tetrahydrobiopterin (BH4)

Micronutrientc

Dietary Referencea

Laboratory Referencea

Responders

Non-responders

Responders

Non-responders

# met / # not metb

# met / # not metb

# met / # not metb

# met / # not metb

Baseline

Endpoint

Baseline

Endpoint

Baseline

Endpoint

Baseline

Endpoint

Vitamin B6

15/2

12/5

14/1

12/2

17/0

18/0

14/0

12/0

Vitamin B12

16/1

11/6

13/2

11/3

16/2

17/1

13/2

13/2

Folate

14/3

10/7

15/0

12/2

11/0d

18/0

14/0

15/0

Iron

13/4

10/7

14/1

13/1

17/0

17/1

13/2

14/1

  1. DRI dietary reference intake
  2. aDietary reference met based on reported 3-day diet record analysis. Laboratory reference met based on measurements from Quest Diagnostics, assessed as above minimum level
  3. bMissing values not reported
  4. cNo statistically significant difference between no. meeting DRI guidelines at start vs. endpoint, by Fisher’s exact test, p = 0.05
  5. d7 missing values for laboratory folate at baseline due to laboratory error
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Orphanet Journal of Rare Diseases

ISSN: 1750-1172